Human MelanA (MLANA) activation kit by CRISPRa

SKU GA101624

MLANA CRISPRa kit - CRISPR gene activation of human melan-A

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: MLANA
• Locus ID: 2315
• Components:

  GA101624G1, MelanA gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101624G2, MelanA gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101624G3, MelanA gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_005511
• UniProt ID: Q16655
• Synonyms: MART-1; MART1
• Summary: Involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage II melanosomes.[UniProtKB/Swiss-Prot Function]