Human Flamingo homolog 1 (CELSR3) activation kit by CRISPRa

SKU GA101350

CELSR3 CRISPRa kit - CRISPR gene activation of human cadherin EGF LAG seven-pass G-type receptor 3

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: CELSR3
• Locus ID: 1951
• Components:

  GA101350G1, Flamingo homolog 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101350G2, Flamingo homolog 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101350G3, Flamingo homolog 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001407
• UniProt ID: Q9NYQ7
• Synonyms: ADGRC3; CDHF11; EGFL1; FMI1; HFMI1; MEGF2; RESDA1
• Summary: This gene belongs to the flamingo subfamily, which is included in the cadherin superfamily. The flamingo cadherins consist of nonclassic-type cadherins that do not interact with catenins. They are plasma membrane proteins containing seven epidermal growth factor-like repeats, nine cadherin domains and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic feature of their subfamily. The encoded protein may be involved in the regulation of contact-dependent neurite growth and may play a role in tumor formation. [provided by RefSeq, Jun 2013]