Human N Cadherin (CDH2) activation kit by CRISPRa

SKU GA100714

CDH2 CRISPRa kit - CRISPR gene activation of human cadherin 2

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: CDH2
• Locus ID: 1000
• Components:

  GA100714G1, N Cadherin gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100714G2, N Cadherin gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100714G3, N Cadherin gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001308176, NM_001792
• UniProt ID: P19022
• Synonyms: CD325; CDHN; CDw325; NCAD
• Summary: This gene encodes a classical cadherin and member of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein is proteolytically processed to generate a calcium-dependent cell adhesion molecule and glycoprotein. This protein plays a role in the establishment of left-right asymmetry, development of the nervous system and the formation of cartilage and bone. [provided by RefSeq, Nov 2015]