TGF beta Receptor I (TGFBR1) (NM_004612) Human Tagged ORF Clone Lentiviral Particle

SKU
RC219514L1V
Lenti ORF particles, TGFBR1 (Myc-DDK tagged) - Human transforming growth factor, beta receptor 1 (TGFBR1), transcript variant 1, 200ul, >10^7 TU/mL
  • LentiORF®
    LentiORF®

    Expression-ready ORF plasmid in lenti backbone

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    Ready-to-use Lentiviral Particles

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$1,252.00
2 Weeks*
Specifications
Product Data
Tag Myc-DDK
Target Symbol TGF beta Receptor I
Synonyms AAT5; ACVRLK4; ALK-5; ALK5; ESS1; LDS1; LDS1A; LDS2A; MSSE; SKR4; tbetaR-I; TBR-i; TBRI; TGFR-1
Vector pLenti-C-Myc-DDK
Mammalian Cell Selection None
Sequence Data
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC219514).
ACCN NM_004612
ORF Size 1509 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Shipping Dry Ice
Reference Data
RefSeq NM_004612.2
RefSeq Size 6475 bp
RefSeq ORF 1512 bp
Locus ID 7046
UniProt ID P36897
Cytogenetics 9q22.33
Domains Activin_recp, GS, pkinase, S_TKc, TyrKc
Protein Families Druggable Genome, Protein Kinase, Transmembrane
Protein Pathways Adherens junction, Chronic myeloid leukemia, Colorectal cancer, Cytokine-cytokine receptor interaction, Endocytosis, MAPK signaling pathway, Pancreatic cancer, Pathways in cancer, TGF-beta signaling pathway
MW 55.96 kDa
Summary The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.