MAGI3 (NM_152900) Human Tagged ORF Clone Lentiviral Particle

SKU RC218925L3V

Lenti ORF particles, MAGI3 (Myc-DDK tagged) - Human membrane associated guanylate kinase, WW and PDZ domain containing 3 (MAGI3), transcript variant 2, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: MAGI3
• Synonyms: dJ730K3.2; MAGI-3
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC218925).
• ACCN: NM_152900
• ORF Size: 3375 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_152900.1
• RefSeq Size: 7221 bp
• RefSeq ORF: 3378 bp
• Locus ID: 260425
• UniProt ID: Q5TCQ9
• Cytogenetics: 1p13.2
• Protein Families: Druggable Genome
• Protein Pathways: Tight junction
• MW: 123.3 kDa
• Summary: Acts as a scaffolding protein at cell-cell junctions, thereby regulating various cellular and signaling processes. Cooperates with PTEN to modulate the kinase activity of AKT1. Its interaction with PTPRB and tyrosine phosphorylated proteins suggests that it may link receptor tyrosine phosphatase with its substrates at the plasma membrane. In polarized epithelial cells, involved in efficient trafficking of TGFA to the cell surface. Regulates the ability of LPAR2 to activate ERK and RhoA pathways. Regulates the JNK signaling cascade via its interaction with FZD4 and VANGL2.[UniProtKB/Swiss-Prot Function]