MSRB2 (NM_012228) Human Tagged ORF Clone Lentiviral Particle

SKU RC215002L3V

Lenti ORF particles, MSRB2 (Myc-DDK-tagged)-Human methionine sulfoxide reductase B2 (MSRB2), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: MSRB2
• Synonyms: CBS-1; CBS1; CGI-131; MSRB; PILB
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC215002).
• ACCN: NM_012228
• ORF Size: 603 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_012228.2, NP_036360.2
• RefSeq Size: 903 bp
• RefSeq ORF: 549 bp
• Locus ID: 22921
• UniProt ID: Q9Y3D2
• Cytogenetics: 10p12.2
• Domains: SelR
• Protein Families: Transcription Factors
• MW: 21.47 kDa
• Summary: Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases, methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residue. Upon oxidative stress, may play a role in the preservation of mitochondrial integrity by decreasing the intracellular reactive oxygen species build-up through its scavenging role, hence contributing to cell survival and protein maintenance.[UniProtKB/Swiss-Prot Function]