Sulfatase 2 (SULF2) (NM_018837) Human Tagged ORF Clone Lentiviral Particle

SKU RC212675L1V

Lenti ORF particles, SULF2 (Myc-DDK tagged) - Human sulfatase 2 (SULF2), transcript variant 1, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: Sulfatase 2
• Synonyms: HSULF-2
• Vector: pLenti-C-Myc-DDK
• Mammalian Cell Selection: None
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC212675).
• ACCN: NM_018837
• ORF Size: 2610 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_018837.2
• RefSeq Size: 3909 bp
• RefSeq ORF: 2613 bp
• Locus ID: 55959
• UniProt ID: Q8IWU5
• Cytogenetics: 20q13.12
• Protein Families: Druggable Genome, Transmembrane
• MW: 100.5 kDa
• Summary: Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 [PubMed 16192265]).[supplied by OMIM, Mar 2008]