RBM5 (NM_005778) Human Tagged ORF Clone Lentiviral Particle

SKU RC212543L1V

Lenti ORF particles, RBM5 (Myc-DDK tagged) - Human RNA binding motif protein 5 (RBM5), transcript variant 1, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: RBM5
• Synonyms: G15; H37; LUCA-15; LUCA15; RMB5
• Vector: pLenti-C-Myc-DDK
• Mammalian Cell Selection: None
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC212543).
• ACCN: NM_005778
• ORF Size: 2445 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_005778.1, NP_005769.1
• RefSeq Size: 3135 bp
• RefSeq ORF: 2448 bp
• Locus ID: 10181
• UniProt ID: P52756
• Cytogenetics: 3p21.31
• Domains: G-patch, RRM, zf-C2H2, zf-RanBP
• Protein Families: Druggable Genome
• MW: 92 kDa
• Summary: This gene is a candidate tumor suppressor gene which encodes a nuclear RNA binding protein that is a component of the spliceosome A complex. The encoded protein plays a role in the induction of cell cycle arrest and apoptosis through pre-mRNA splicing of multiple target genes including the tumor suppressor protein p53. This gene is located within the tumor suppressor region 3p21.3, and may play a role in the inhibition of tumor transformation and progression of several malignancies including lung cancer. [provided by RefSeq, Oct 2011]