PRPF8 (NM_006445) Human Tagged ORF Clone Lentiviral Particle

SKU RC209472L1V

Lenti ORF particles, PRPF8 (Myc-DDK tagged) - Human PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae) (PRPF8), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: PRPF8
• Synonyms: HPRP8; PRP8; PRPC8; RP13; SNRNP220
• Vector: pLenti-C-Myc-DDK
• Mammalian Cell Selection: None
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC209472).
• ACCN: NM_006445
• ORF Size: 7005 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_006445.3
• RefSeq Size: 7311 bp
• RefSeq ORF: 7008 bp
• Locus ID: 10594
• UniProt ID: Q6P2Q9
• Cytogenetics: 17p13.3
• Domains: JAB_MPN
• Protein Families: Druggable Genome
• Protein Pathways: Spliceosome
• MW: 273.4 kDa
• Summary: Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa. [provided by RefSeq, Jul 2008]