Shwachman Bodian Diamond syndrome (SBDS) (NM_016038) Human Tagged ORF Clone Lentiviral Particle

SKU RC208964L3V

Lenti ORF particles, SBDS (Myc-DDK tagged) - Human Shwachman-Bodian-Diamond syndrome (SBDS), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: Shwachman Bodian Diamond syndrome
• Synonyms: CGI-97; SDO1; SDS; SWDS
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC208964).
• ACCN: NM_016038
• ORF Size: 750 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_016038.2
• RefSeq Size: 1605 bp
• RefSeq ORF: 753 bp
• Locus ID: 51119
• UniProt ID: Q9Y3A5
• Cytogenetics: 7q11.21
• Domains: UPF0023
• MW: 28.8 kDa
• Summary: This gene encodes a highly conserved protein that plays an essential role in ribosome biogenesis. The encoded protein interacts with elongation factor-like GTPase 1 to disassociate eukaryotic initiation factor 6 from the late cytoplasmic pre-60S ribosomal subunit allowing assembly of the 80S subunit. Mutations within this gene are associated with the autosomal recessive disorder Shwachman-Bodian-Diamond syndrome. This gene has a closely linked pseudogene that is distally located. [provided by RefSeq, Jan 2017]