Plexin A4 (PLXNA4) (NM_181775) Human Tagged ORF Clone Lentiviral Particle

SKU RC206375L1V

Lenti ORF particles, PLXNA4 (Myc-DDK tagged) - Human plexin A4 (PLXNA4), transcript variant 2, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: Plexin A4
• Synonyms: FAYV2820; PLEXA4; PLXNA4A; PLXNA4B; PRO34003
• Vector: pLenti-C-Myc-DDK
• Mammalian Cell Selection: None
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC206375).
• ACCN: NM_181775
• ORF Size: 1566 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_181775.2, NP_861440.1
• RefSeq Size: 2020 bp
• RefSeq ORF: 1569 bp
• Locus ID: 91584
• UniProt ID: Q9HCM2
• Cytogenetics: 7q32.3
• Protein Families: Druggable Genome
• MW: 58.1 kDa
• Summary: Coreceptor for SEMA3A. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance in the developing nervous system. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm (By similarity).[UniProtKB/Swiss-Prot Function]