STAM2 (NM_005843) Human Tagged ORF Clone Lentiviral Particle

SKU RC206279L1V

Lenti ORF particles, STAM2 (Myc-DDK tagged) - Human signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 (STAM2), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: STAM2
• Synonyms: Hbp; STAM2A; STAM2B
• Vector: pLenti-C-Myc-DDK
• Mammalian Cell Selection: None
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC206279).
• ACCN: NM_005843
• ORF Size: 1575 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_005843.3
• RefSeq Size: 5701 bp
• RefSeq ORF: 1578 bp
• Locus ID: 10254
• UniProt ID: O75886
• Cytogenetics: 2q23.3
• Domains: SH3, UIM, VHS
• Protein Pathways: Endocytosis, Jak-STAT signaling pathway
• MW: 58.2 kDa
• Summary: The protein encoded by this gene is closely related to STAM, an adaptor protein involved in the downstream signaling of cytokine receptors, both of which contain a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM). Similar to STAM, this protein acts downstream of JAK kinases, and is phosphorylated in response to cytokine stimulation. This protein and STAM thus are thought to exhibit compensatory effects on the signaling pathway downstream of JAK kinases upon cytokine stimulation. [provided by RefSeq, Jul 2008]