CYP1B1 (NM_000104) Human Tagged ORF Clone Lentiviral Particle

SKU RC204074L1V

Lenti ORF particles, CYP1B1 (Myc-DDK tagged) - Human cytochrome P450, family 1, subfamily B, polypeptide 1 (CYP1B1), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: CYP1B1
• Synonyms: ASGD6; CP1B; CYPIB1; GLC3A; P4501B1
• Vector: pLenti-C-Myc-DDK
• Mammalian Cell Selection: None
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC204074).
• ACCN: NM_000104
• ORF Size: 1629 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_000104.2, NP_000095.1
• RefSeq Size: 5160 bp
• RefSeq ORF: 1632 bp
• Locus ID: 1545
• UniProt ID: Q16678
• Cytogenetics: 2p22.2
• Domains: p450
• Protein Families: Druggable Genome, P450
• Protein Pathways: Metabolism of xenobiotics by cytochrome P450, Tryptophan metabolism
• MW: 60.8 kDa
• Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma; therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid. [provided by RefSeq, Jul 2008]