ZNF346 (NM_012279) Human Tagged ORF Clone Lentiviral Particle

SKU RC202856L1V

Lenti ORF particles, ZNF346 (Myc-DDK tagged) - Human zinc finger protein 346 (ZNF346), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: ZNF346
• Synonyms: JAZ; Zfp346
• Vector: pLenti-C-Myc-DDK
• Mammalian Cell Selection: None
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC202856).
• ACCN: NM_012279
• ORF Size: 882 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_012279.2
• RefSeq Size: 3089 bp
• RefSeq ORF: 885 bp
• Locus ID: 23567
• UniProt ID: Q9UL40
• Cytogenetics: 5q35.2
• Domains: zf-C2H2, ZnF_U1
• Protein Families: Druggable Genome
• MW: 32.9 kDa
• Summary: The protein encoded by this gene is a nucleolar, zinc finger protein that preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids, rather than DNA alone. Mutational studies indicate that the zinc finger domains are not only essential for dsRNA binding, but are also required for its nucleolar localization. The encoded protein may be involved in cell growth and survival. It plays a role in protecting neurons by inhibiting cell cycle re-entry via stimulation of p21 gene expression. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2015]