HAND1 (NM_004821) Human Tagged ORF Clone Lentiviral Particle
SKU
RC200513L3V
Lenti ORF particles, HAND1 (Myc-DDK tagged) - Human heart and neural crest derivatives expressed 1 (HAND1), 200ul, >10^7 TU/mL
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
---|---|
Tag | Myc-DDK |
Target Symbol | HAND1 |
Synonyms | bHLHa27; eHand; Hxt; Thing1 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
Mammalian Cell Selection | Puromycin |
Sequence Data |
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC200513).
|
ACCN | NM_004821 |
ORF Size | 645 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Shipping | Dry Ice |
Reference Data | |
RefSeq | NM_004821.1 |
RefSeq Size | 1750 bp |
RefSeq ORF | 648 bp |
Locus ID | 9421 |
UniProt ID | O96004 |
Cytogenetics | 5q33.2 |
Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Transcription Factors |
MW | 23.4 kDa |
Summary | The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, it has been suggested that this transcription factor may be required for early trophoblast differentiation. [provided by RefSeq, Jul 2008] |
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