ELAVL1 (NM_001419) Human Tagged ORF Clone
SKU
RC201562
ELAVL1 (Myc-DDK-tagged)-Human ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) (ELAVL1)
$289.00
$300.00
In Stock*
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
|---|---|
| Target Symbol | ELAVL1 |
| Synonyms | ELAV1; Hua; HUR; MelG |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Chromatograms |
Chromatograms
 Sequencher program is needed, download here |
| Restriction Sites |
SgfI-MluI Cloning Scheme for this gene
|
Plasmid Map
|
| ACCN | NM_001419 |
| ORF Size | 978 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_001419.3 |
| RefSeq Size | 6075 bp |
| RefSeq ORF | 981 bp |
| Locus ID | 1994 |
| UniProt ID | Q15717 |
| Cytogenetics | 19p13.2 |
| Domains | RRM |
| MW | 36.1 kDa |
| Summary | The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy. provided by RefSeq, Sep 2012 |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_001419" in other vectors (7)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| RC201562L1 | Lenti ORF clone of Human ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) (ELAVL1), Myc-DDK-tagged | 10 ug |
$600.00
|
|
| RC201562L2 | Lenti ORF clone of Human ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) (ELAVL1), mGFP tagged | 10 ug |
$600.00
|
|
| RC201562L3 | Lenti ORF clone of Human ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) (ELAVL1), Myc-DDK-tagged | 10 ug |
$600.00
|
|
| RC201562L4 | Lenti ORF clone of Human ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) (ELAVL1), mGFP tagged | 10 ug |
$600.00
|
|
| RG201562 | ELAVL1 (tGFP-tagged) - Human ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) (ELAVL1) | 10 ug |
$489.00
$500.00
|
|
| SC119271 | ELAVL1 (untagged)-Human ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) (ELAVL1) | 10 ug |
$300.00
|
|
| SC322158 | ELAVL1 (untagged)-Human ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) (ELAVL1) | 10 ug |
$300.00
|
|
Citations
Human-Specific Suppression of Hepatic Fatty Acid Catabolism by RNA-Binding Protein HuR
Takaoka, Jaso-Vera, Ruan
bioRxiv (2025)
Takaoka, Jaso-Vera, Ruan
bioRxiv (2025)
AI Summary: OriGene’s pCMV6-hHuR plasmid (Cat# RC201562) was used to overexpress human HuR in cultured cells, enabling the authors to investigate HuR’s human-specific role in suppressing fatty acid catabolism gene expression.
Snippet: Cells were transfected with 400 ng of pCMV6-hHuR (OriGene Cat# RC201562), 100 ng of pCDNA3.1-hPPARα (Addgene Cat# 169019), 100 ng of pSG5-mPPARα (Addgene Cat# 22751), or equal amounts of the corresponding empty plasmid using Lipofectamine 2000 according to the manufacturer's protocol
In vivo functional analysis of non-conserved human lncRNAs associated with cardiometabolic traits
Ruan, Li, Chen et al
Nat Commun (2020) 11 (1), 45 DOI: 10.1038/s41467-019-13688-z
Ruan, Li, Chen et al
Nat Commun (2020) 11 (1), 45 DOI: 10.1038/s41467-019-13688-z
Cited by 125
AI Summary: OriGene products, specifically the HuR (ELAVL1) shRNA lentiviral particles (TL311616V) and HuR (ELAVL1) antibody (TA500053), were used in this study to experimentally knock down and detect HuR protein, enabling the authors to validate the interaction between the lncRNA LINC01018 and HuR in regulating gene expression related to fatty acid oxidation in humanized mouse livers.
Human antigen R protein modulates vascular endothelial growth factor expression in human corneal epithelial cells under hypoxia
Hung, Sun, Liou et al
J. Formos. Med. Assoc. (2019) 119 (1 Pt 2), 359-366 DOI: 10.1016/j.jfma.2019.06.006
Hung, Sun, Liou et al
J. Formos. Med. Assoc. (2019) 119 (1 Pt 2), 359-366 DOI: 10.1016/j.jfma.2019.06.006
AI Summary: OriGene's ELAVL1 (Myc-DDK-tagged)-human cDNA clone (#RC201562) was used in this study to overexpress the HuR protein and investigate its role in regulating VEGF expression under hypoxic conditions in human corneal epithelial cells.
Snippet: The ELAVL1 (Myc-DDK-tagged)-human cDNA clones were purchased from OriGene Technologies (#RC201562, Rockville, MD, USA) and amplified by RBC HIT competent cells DH5α (#RH617, RBC Bioscience, New Taipei City, Taiwan);The ELAVL1 (Myc-DDK-tagged)-human cDNA clones were purchased from OriGene Technologies (#RC201562, Rockville, MD, U.S.A.) and amplified by RBC HIT competent cells DH5α (#RH617, RBC Bioscience, New Taipei City, Taiwan)
Dysregulation of tristetraprolin and human antigen R promotes gastric cancer progressions partly by upregulation of the high-mobility group box 1
Wang, Chen, Guo et al
Sci Rep (2018) 8 (1), 7080 DOI: 10.1038/s41598-018-25443-3
Wang, Chen, Guo et al
Sci Rep (2018) 8 (1), 7080 DOI: 10.1038/s41598-018-25443-3
AI Summary: In this study, OriGene’s pCMV6-HuR (RC201562) expression plasmid and pCMV6-Entry (PS100001) empty vector were used to manipulate HuR expression in gastric cancer cells, enabling the researchers to investigate the role of HuR in cancer progression.
Snippet: … The pCMV6-HuR (RC201562) expression plasmids as well as the pCMV6-Entry (PS100001) empty vector were purchased from OriGene (OriGene Technologies, Beijing, China). …
In vivo functional analysis of non-conserved human lncRNAs associated with cardiometabolic traits
Ruan, Li, Chen et al
researchgate.net (2019)
Ruan, Li, Chen et al
researchgate.net (2019)
Showing 1-5 of 5 papers.
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