C14orf130 (UBR7) Human siRNA Oligo Duplex (Locus ID 55148)

SKU SR310526

UBR7 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each

Product Data

• Purity: HPLC purified
• Quality Control: Tested by ESI-MS
• Sequences: Available with shipment
• Components:
  UBR7 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 55148); Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol; Included - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml

  Once you identified the best-performing siRNA sequence of the kit, you can order a single siRNA individually.

  Cat#	SRXXXXXX followed by A, B or C, then add L; For example, for sequence A of SR300003, the SKU is SR300003AL.
  Description	10 nmol of siRNA of the above specified vial, scramble control NOT included
  Price	$/€ 375 per vial

  If you want to order 20 nmol, please order quantity of 2 units.; If you need negative control, please order SR30004 (2 nmol of scramble siRNA control)
  Need an individual siRNA?
• Stability: One year from date of shipment when stored at -20°C.
• Shipping: Ambient
• # of Transfections: Approximately 330 transfections/2nmol in 24-well plate under optimized conditions (final conc. 10 nM).
• Note: Single siRNA duplex (10nmol) can be ordered.

Reference Data

• RefSeq: NM_001100417, NM_018108, NM_175748, NR_038150
• UniProt ID: Q8N806
• Synonyms: C14orf130; FLJ10483; MGC9518
• Summary: This gene encodes a UBR box-containing protein that belongs to the E3 ubiquitin ligase family. The protein also contains a plant homeodomain (PHD) in the C-terminus. In mammals, the encoded protein recognizes N-degrons, the destabilizing N-terminal residues of short-lived proteins, which results in ubiquitinylation, and proteolysis via the proteasome. [provided by RefSeq, Jul 2016]
• Performance Guaranteed: OriGene guarantees that at least two of the three Dicer-Substrate duplexes in the kit will provide at least 70% or more knockdown of the target mRNA when used at 10 nM concentration by quantitative RT-PCR when the TYE-563 fluorescent transfection control duplex (cat# SR30002) indicates that >90% of the cells have been transfected and the HPRT positive control (cat# SR30003) provides 90% knockdown efficiency.; ; For non-conforming siRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the siRNA kit. To arrange for a free replacement with newly designed duplexes, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled siRNA control (quantitative RT-PCR data required).