Prom1 Mouse shRNA Plasmid (Locus ID 19126)

SKU TL501745

Prom1 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided

Product Data

• Locus ID: 19126
• Synonyms: 4932416E19Rik; AC133; CD133; Prom; Prom-1; Proml1
• Vector: pGFP-C-shLenti
• E. coli Selection: Chloramphenicol (34 ug/ml)
• Format: Lentiviral plasmids
• Components: Prom1 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 19126). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
• RefSeq: BC028286, NM_001163577, NM_001163578, NM_001163581, NM_001163582, NM_001163583, NM_001163584, NM_001163585, NM_008935, NM_001163585.1, NM_008935.1, NM_008935.2, NM_001163577.1, NM_001163578.1, NM_001163581.1, NM_001163582.1, NM_001163583.1, NM_001163584.1
• UniProt ID: O54990
• Summary: May play a role in cell differentiation, proliferation and apoptosis. Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis (PubMed:19228982). Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner.[UniProtKB/Swiss-Prot Function]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient