ATG5 Human shRNA Plasmid Kit (Locus ID 9474)

SKU TL314610

ATG5 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided

Product Data

• Locus ID: 9474
• Synonyms: APG5; APG5-LIKE; APG5L; ASP; hAPG5; SCAR25
• Vector: pGFP-C-shLenti
• E. coli Selection: Chloramphenicol (34 ug/ml)
• Format: Lentiviral plasmids
• Components: ATG5 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 9474). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
• RefSeq: NM_001286106, NM_001286107, NM_001286108, NM_001286111, NM_004849, NR_104402, NR_104403, NM_004849.1, NM_004849.2, NM_004849.3, NM_001286111.1, NM_001286107.1, NM_001286108.1, NM_001286106.1, BC093011, BC093011.1, BC002699, BM831472, NM_004849.4
• UniProt ID: Q9H1Y0
• Summary: The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. Several transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Sep 2015]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient