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ATG5 Rabbit Polyclonal Antibody

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SKU
TA301481
Rabbit Polyclonal Antibody against ATG5
Size:
100 ul
Conjugation:
Unconjugated
  $680.00
2 Weeks*
Bulk/Customize

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View other "ATG5 or NM_004849" antibodies

Specifications
Specifications
Product Data
Application Electron Microscopy, ELISA, FC, ICC/IF, IHC, Immunoblotting, IP, Simple Western, WB
Recommended Dilution Radioimmunoassay, ELISA, Immunoblotting, Knockout Validated, Knockdown Validated, Electron Microscopy, Flow Cytometry, Western Blot: 1:500, Simple Western: 1:50, Immunocytochemistry/ Immunofluorescence: 1:250, Immunohistochemistry: 1:400, Immunohistochemistry-Paraffin: 1:400, Immunoprecipitation: 1:10 - 1:500, Proximity Ligation Assay
Reactivity Cow, Human, Mouse, Porcine, Primate, Rat, Xenopus, Zebrafish
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen A synthetic peptide made to an N-terminal region (within residues 1-50) of the human ATG5 protein. Swiss-Prot# Q9H1Y0
Buffer PBS plus 30% glycerol and 0.1% sodium azide
Concentration lot specific
Purification peptide affinity purified
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Gene Name autophagy related 5
Database Link
Background Autophagy is an important mechanism for nonselective intracellular breakdown whereby cytosol and organelles are encapsulated in vesicles, which are then engulfed and digested by lytic vacuoles/lysosomes. ATG5 is required for autophagy. It conjugates to ATG12 and associates with isolation membrane to form autophagosomes. The conjugate detaches from the membrane immediately before or after autophagosome formation is completed. Conjugation to ATG12 is essential for autophagy, but is not required for association with isolation membrane. ATG5 also plays an important role in the apoptotic process. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity.
Synonyms APG5; APG5-LIKE; APG5L; ASP; hAPG5
Reference Data
Protein Categories Cytokines, Intracellular Proteins, Nervous system: Neurodegenerative diseases
Protein Families Druggable Genome
Protein Pathways Regulation of autophagy, RIG-I-like receptor signaling pathway
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.