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S100 beta (S100B) (NM_006272) Human Recombinant Protein

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SKU
TP750189
Purified recombinant protein of Human S100 calcium binding protein B (S100B),full length, tag free, expressed in E.coli, 50ug
Size:
50 ug
  $380.00
In Stock*
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Frequently Bought Together (1)

TA700560 S100B Biotinylated Detection Mouse Monoclonal antibody, clone OTI3G6 50 ug
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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding the full-length of S100B
Tag Tag Free
Predicted MW 10.7 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_006263
Locus ID 6285
UniProt ID P04271
Cytogenetics 21q22.3
RefSeq Size 1135
RefSeq ORF 276
Synonyms NEF; S100; S100-B; S100beta
Summary The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes. provided by RefSeq, Jul 2008
Protein Categories Intracellular Proteins
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Other "S100 beta" proteins (4)
SKU Description Size Price
PH300277 S100B MS Standard C13 and N15-labeled recombinant protein (NP_006263) 10 ug
$3,360.00
LC416735 Lyophilized S100B HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY416735 Transient overexpression lysate of S100 calcium binding protein B (S100B) (as WB positive control) 100 ug
$436.00
TP300277 Recombinant protein of human S100 calcium binding protein B (S100B), 20 µg 20 ug
$737.00

file-alt Citations

Stromal expression of hemopexin is associated with lymph-node metastasis in pancreatic ductal adenocarcinoma
Suzuki, Takadate, Mizuma et al
PLoS ONE (2020) 15 (7), e0235904 DOI: 10.1371/journal.pone.0235904
Cited by 21
AI Summary: OriGene’s ABHD14B antibody (ABHD14B, OriGene Technologies GmbH) was used for immunohistochemical analysis to investigate protein expression in the tumor stroma of pancreatic ductal adenocarcinoma patients.
Snippet: Sections were incubated (overnight, 4°C) with primary antibodies against AGR3 (1:2000, Abnova Co., Taipei, Taiwan), DEF3 (1:200, Abnova Co.), MYH14 (1:300, Novus Biologicals, Littleton, CO, USA), ABHD14B (1:250, OriGene Technologies GmbH, Herford Cached
FigureFigureFigure
IHC
Adult neurogenesis and gliogenesis in the dorsal and ventral canine hippocampus
Bekiari, Grivas, Tsingotjidou et al
J. Comp. Neurol. (2019)
AI Summary: OriGene contributed to this study by providing the rabbit polyclonal anti-calbindin/CALB1 antibody (#TA342845), which was used to identify and analyze calbindin-expressing cells in the canine hippocampus during investigations of adult neurogenesis and gliogenesis.
Snippet: Millipore;#AB149;RRID: ΑΒ_2307441), anti - calbindin/CALB1 (rabbit polyclonal;1:50;Origene;staining on human cerebellum neurons (Millipore antibody datasheet). The rabbit polyclonal anti - calbindin/CALB1 (Origene;#TA342845) antibody was raised
A multimodal RAGE-specific inhibitor reduces amyloid β-mediated brain disorder in a mouse model of Alzheimer disease
Deane, Singh, Sagare et al
J. Clin. Invest. (2012) 122 (4), 1377-92 DOI: 10.1172/JCI58642
Cited by 41
AI Summary: In this study, OriGene's RAGE expression plasmid (Cat# RC210438) was used to generate RAGE-expressing cells for in vitro experiments assessing the inhibitory effects of FPS-ZM1 on amyloid β-induced cellular stress.
Snippet: RAGE contains an extracellular V domain that binds multiple ligands, including advanced glycation end products (AGE) proteins, S100/calgranulins, Aβ and amphoterin, 2 C-type immunoglobulin domains, and a short cytoplasmic domain that is required for RAGE-mediated
Showing 1-3 of 3 papers.
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