Interleukin 34 (IL34) (NM_152456) Human Recombinant Protein

SKU TP723763

Purified recombinant protein of Human interleukin 34 (IL34), transcript variant 1

Product Data

• Species: Human
• Expression Host: CHO
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Human IL-34, the region of Met1 - Pro242, from gene Accession# NM_152456.2 with a C-terminal 8His tag
• Tag: C-His
• Predicted MW: 26.7 kDa
• Concentration: lot specific
• Purity: >95%, as determined by Coomassie stained SDS-PAGE.
• Buffer: 10 mM NaH2PO4, 0.5 M NaCl, pH 7.4
• Bioactivity: Human IL-34 induces MCP-1 (CCL2) production in human peripheral blood mononuclear cells (PBMC) in a dose-dependent manner. The ED50 for this effect is 4 - 20 ng/mL.
• Endotoxin: Less than 0.01 ng per µg protein as determined by the LAL method
• Storage: Store at -80°C.
• Stability: Unopened vial can be stored between 2°C and 8°C for up to 2 weeks, at -20°C for up to 6 months, or at -70°C or below until the expiration date. Aliquots can be stored between 2°C and 8°C for up to one week and stored at -20°C or colder for up to 3 months. Avoid repeated freeze/thaw cycles.
• Shipping: Dry Ice

Reference Data

• RefSeq: NP_689669
• Locus ID: 146433
• UniProt ID: Q6ZMJ4
• Cytogenetics: 16q22.1
• RefSeq Size: 1796
• RefSeq ORF: 726
• Synonyms: C16orf77; IL-34
• Summary: Interleukin-34 is a cytokine that promotes the differentiation and viability of monocytes and macrophages through the colony-stimulating factor-1 receptor (CSF1R; MIM 164770) (Lin et al., 2008 [PubMed 18467591]).[supplied by OMIM, May 2008]