CRYGD (NM_006891) Human Recombinant Protein

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SKU
TP322889
Recombinant protein of human crystallin, gamma D (CRYGD), 20 µg
  $867.00
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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>RC222889 protein sequence
Red=Cloning site Green=Tags(s)

MGKITLYEDRGFQGRHYECSSDHPNLQPYLSRCNSARVDSGCWMLYEQPNYSGLQYFLRRGDYADHQQWM
GLSDSVRSCRLIPHSGSHRIRLYEREDYRGQMIEFTEDCSCLQDRFRFNEIHSLNVLEGSWVLYELSNYR
GRQYLLMPGDYRRYQDWGATNARVGSLRRVIDFS

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-Myc/DDK
Predicted MW 20.6 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_008822
Locus ID 1421
UniProt ID P07320
Cytogenetics 2q33.3
RefSeq Size 724
RefSeq ORF 522
Synonyms CACA; CCA3; CCP; cry-g-D; CRYG4; CTRCT4; PCC
Summary Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. They are differentially regulated after early development. Four gamma-crystallin genes (gamma-A through gamma-D) and three pseudogenes (gamma-E, gamma-F, gamma-G) are tandemly organized in a genomic segment as a gene cluster. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation. provided by RefSeq, Jul 2008
Protein Categories Intracellular Proteins, Nervous system Diseases
Protein Families Druggable Genome
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Other "CRYGD" proteins (3)
SKU Description Size Price
PH322889 CRYGD MS Standard C13 and N15-labeled recombinant protein (NP_008822) 10 ug
$3,360.00
LC416332 Lyophilized CRYGD HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY416332 Transient overexpression lysate of crystallin, gamma D (CRYGD) (as WB positive control) 100 ug
$436.00

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