TBX1 (NM_080647) Human Recombinant Protein

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SKU
TP316204
Purified recombinant protein of Homo sapiens T-box 1 (TBX1), transcript variant C, 20 µg
  $867.00
4 Weeks*
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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>RC216204 representing NM_080647
Red=Cloning site Green=Tags(s)

MHFSTVTRDMEAFTASSLSSLGAAGGFPGAASPGADPYGPREPPPPPRYDPCAAAAPGAPGPPPPPHAYP
FAPAAGAATSAAAEPEGPGASCAAAAKAPVKKNAKVAGVSVQLEMKALWDEFNQLGTEMIVTKAGRRMFP
TFQVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWLVAGKADPATPGRVHYHPDSPAKGAQWMKQIV
SFDKLKLTNNLLDDNGHIILNSMHRYQPRFHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHRI
TQLKIASNPFAKGFRDCDPEDWPRNHRPGALPLMSAFARSRNPVASPTQPSGTEKDAAEARREFQRDAGG
PAVLGDPAHPPQLLARVLSPSLPGAGGAGGLVPLPGAPGGRPSPPNPELRLEAPGASEPLHHHPYKYPAA
AYDHYLGAKSRPAPYPLPGLRGHGYHPHAHPHHHHHPVSPAAAAAAAAAAAAAAANMYSSAGAAPPGSYD
YCPR

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-Myc/DDK
Predicted MW 52.5 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_542378
Locus ID 6899
UniProt ID O43435
Cytogenetics 22q11.21
RefSeq Size 2082
RefSeq ORF 1482
Synonyms CAFS; CATCH22; CTHM; DGCR; DGS; DORV; TBX1C; TGA; VCF; VCFS
Summary This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product shares 98% amino acid sequence identity with the mouse ortholog. DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS), a common congenital disorder characterized by neural-crest-related developmental defects, has been associated with deletions of chromosome 22q11.2, where this gene has been mapped. Studies using mouse models of DiGeorge syndrome suggest a major role for this gene in the molecular etiology of DGS/VCFS. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. provided by RefSeq, Jul 2008
Protein Categories Growth Factors, Immune system diseases, Intracellular Proteins, Transciption Factors
Protein Families Transcription Factors
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Other "TBX1" proteins (7)
SKU Description Size Price
PH314605 TBX1 MS Standard C13 and N15-labeled recombinant protein (NP_542377) 10 ug
$3,360.00
PH316204 TBX1 MS Standard C13 and N15-labeled recombinant protein (NP_542378) 10 ug
$3,360.00
LC409116 Lyophilized TBX1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC409117 Lyophilized TBX1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY409116 Transient overexpression lysate of T-box 1 (TBX1), transcript variant A (as WB positive control) 100 ug
$436.00
LY409117 Transient overexpression lysate of T-box 1 (TBX1), transcript variant C (as WB positive control) 100 ug
$665.00
TP314605 Recombinant protein of human T-box 1 (TBX1), transcript variant A, 20 µg 20 ug
$867.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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