TMS1(PYCARD) (NM_013258) Human Recombinant Protein

CAT#: TP315592

Recombinant protein of human PYD and CARD domain containing (PYCARD), transcript variant 1


 Product Datasheet for 'TP315592'

  View other "PYCARD" proteins (9)

USD 748.00


Availability*
2 Weeks

Size
    • 20 ug


Product images

Specifications

Product Data
Description Recombinant protein of human PYD and CARD domain containing (PYCARD), transcript variant 1
Species Human
Expression Host HEK293T
Expression cDNA Clone or AA Sequence Recombinant protein was produced with TrueORF clone, RC215592. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag C-MYC/DDK
Predicted MW 21.4 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. Store at –80C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_037390
Locus ID 29108
Refseq Size 936
Cytogenetics 16p11.2
Refseq ORF 585
Synonyms ASC; CARD5; TMS; TMS-1; TMS1
Summary This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome
Protein Pathways NOD-like receptor signaling pathway, Cytosolic DNA-sensing pathway

Documents

Other Versions

Other products for "PYCARD"
Frequently bought together (2)
Clone OTI4C5, Anti-DDK (FLAG) monoclonal antibody
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PYCARD (TMS1) mouse monoclonal antibody, clone OTI2A7 (formerly 2A7)
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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