CTBP1 (NM_001328) Human Recombinant Protein

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SKU
TP310529
Recombinant protein of human C-terminal binding protein 1 (CTBP1), transcript variant 1, 20 µg
  $867.00
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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>RC210529 protein sequence
Red=Cloning site Green=Tags(s)

MGSSHLLNKGLPLGVRPPIMNGPLHPRPLVALLDGRDCTVEMPILKDVATVAFCDAQSTQEIHEKVLNEA
VGALMYHTITLTREDLEKFKALRIIVRIGSGFDNIDIKSAGDLGIAVCNVPAASVEETADSTLCHILNLY
RRATWLHQALREGTRVQSVEQIREVASGAARIRGETLGIIGLGRVGQAVALRAKAFGFNVLFYDPYLSDG
VERALGLQRVSTLQDLLFHSDCVTLHCGLNEHNHHLINDFTVKQMRQGAFLVNTARGGLVDEKALAQALK
EGRIRGAALDVHESEPLSFSQGPLKDAPNLICTPHAAWYSEQASIEMREEAAREIRRAITGRIPDSLKNC
VNKDHLTAATHWASMDPAVVHPELNGAAYRYPPGVVGVAPTGIPAAVEGIVPSAMSLSHGLPPVAHPPHA
PSPGQTVKPEADRDHASDQL

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-Myc/DDK
Predicted MW 47.4 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_001319
Locus ID 1487
UniProt ID Q13363
Cytogenetics 4p16.3
RefSeq Size 2288
RefSeq ORF 1320
Synonyms BARS; HADDTS
Summary This gene encodes a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants. provided by RefSeq, Jul 2008
Protein Categories Intracellular Proteins
Protein Pathways Chronic myeloid leukemia, Notch signaling pathway, Pathways in cancer, Wnt signaling pathway
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Other "CTBP1" proteins (7)
SKU Description Size Price
PH308594 CTBP1 MS Standard C13 and N15-labeled recombinant protein (NP_001012632) 10 ug
$3,360.00
PH310529 CTBP1 MS Standard C13 and N15-labeled recombinant protein (NP_001319) 10 ug
$3,360.00
LC400528 Lyophilized CTBP1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC422883 Lyophilized CTBP1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY400528 Transient overexpression lysate of C-terminal binding protein 1 (CTBP1), transcript variant 1 (as WB positive control) 100 ug
$436.00
LY422883 Transient overexpression lysate of C-terminal binding protein 1 (CTBP1), transcript variant 2 (as WB positive control) 100 ug
$436.00
TP308594 Recombinant protein of human C-terminal binding protein 1 (CTBP1), transcript variant 2, 20 µg 20 ug
$867.00

file-alt Citations

ZNF750 interacts with KLF4 and RCOR1, KDM1A, and CTBP1/2 chromatin regulators to repress epidermal progenitor genes and induce differentiation genes
Boxer, Barajas, Tao et al
Genes Dev. (2014) 28 (18), 2013-26 DOI: 10.1101/gad.246579.114
Cited by 155
AI Summary: OriGene products—including recombinant ZNF750, KLF4, KDM1A, CTBP1, and CTBP2 proteins—were used in this study to investigate the molecular interactions by which ZNF750 regulates epidermal progenitor and differentiation genes.
Snippet: The following recombinant proteins were purchased or purified: ZNF750 (Origene), MBP (Prospec), KLF4 (Origene), RCOR1 (Abnova), KDM1A (Origene), CTBP1 (Origene), CTBP2 (Origene)
Showing 1-1 of 1 papers.
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