GNMT (NM_018960) Human Recombinant Protein

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SKU
TP307497
Recombinant protein of human glycine N-methyltransferase (GNMT), 20 µg
  $867.00
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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>RC207497 protein sequence
Red=Cloning site Green=Tags(s)

MVDSVYRTRSLGVAAEGLPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCQRVLDVACGTGV
DSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANWMTLDKDVPQSAEGGFDAVICLG
NSFAHLPDCKGDQSEHRLALKNIASMVRAGGLLVIDHRNYDHILSTGCAPPGKNIYYKSDLTKDVTTSVL
IVNNKAHMVTLDYTVQVPGAGQDGSPGLSKFRLSYYPHCLASFTELLQAAFGGKCQHSVLGDFKPYKPGQ
TYIPCYFIHVLKRTD

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-Myc/DDK
Predicted MW 32.6 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_061833
Locus ID 27232
UniProt ID Q14749
Cytogenetics 6p21.1
RefSeq Size 1091
RefSeq ORF 885
Synonyms HEL-S-182mP
Summary The protein encoded by this gene is an enzyme that catalyzes the conversion of S-adenosyl-L-methionine (along with glycine) to S-adenosyl-L-homocysteine and sarcosine. This protein is found in the cytoplasm and acts as a homotetramer. Defects in this gene are a cause of GNMT deficiency (hypermethioninemia). Alternative splicing results in multiple transcript variants. Naturally occurring readthrough transcription occurs between the upstream CNPY3 (canopy FGF signaling regulator 3) gene and this gene and is represented with GeneID:107080644. provided by RefSeq, Jan 2016
Protein Categories Intracellular Proteins
Protein Families Druggable Genome
Protein Pathways Glycine, serine and threonine metabolism
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Other "GNMT" proteins (4)
SKU Description Size Price
PH307497 GNMT MS Standard C13 and N15-labeled recombinant protein (NP_061833) 10 ug
$3,360.00
LC412848 Lyophilized GNMT HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY412848 Transient overexpression lysate of glycine N-methyltransferase (GNMT) (as WB positive control) 100 ug
$436.00
TP720534 Recombinant protein of human glycine N-methyltransferase (GNMT) 10 ug
$340.00

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