CTRP4 (C1QTNF4) (NM_031909) Human Recombinant Protein

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TP307458
Recombinant protein of human C1q and tumor necrosis factor related protein 4 (C1QTNF4), 20 µg
  $867.00
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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>RC207458 protein sequence
Red=Cloning site Green=Tags(s)

MLPLLLGLLGPAACWALGPTPGPGSSELRSAFSAARTTPLEGTSEMAVTFDKVYVNIGGDFDVATGQFRC
RVPGAYFFSFTAGKAPHKSLSVMLVRNRDEVQALAFDEQRRPGARRAASQSAMLQLDYGDTVWLRLHGAP
QYALGAPGATFSGYLVYADADADAPARGPPAPPEPRSAFSAARTRSLVGSDAGPGPRHQPLAFDTEFVNI
GGDFDAAAGVFRCRLPGAYFFSFTLGKLPRKTLSVKLMKNRDEVQAMIYDDGASRRREMQSQSVMLALRR
GDAVWLLSHDHDGYGAYSNHGKYITFSGFLVYPDLAPAAPPGLGASELL

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-Myc/DDK
Predicted MW 35.1 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_114115
Locus ID 114900
UniProt ID Q9BXJ3
Cytogenetics 11p11.2
RefSeq Size 1436
RefSeq ORF 987
Synonyms CTRP4; ZACRP4
Summary May be involved in the regulation of the inflammatory network. Its role as pro- or anti-inflammatory seems to be context dependent (PubMed:21658842, PubMed:27086950). Seems to have some role in regulating food intake and energy balance when administered in the brain. This effect is sustained over a two-day period, and it is accompanied by decreased expression of orexigenic neuropeptides in the hypothalamus 3 h post-injection (By similarity).UniProtKB/Swiss-Prot Function
Protein Categories Cytokines, Secreated Proteins
Protein Families Secreted Protein
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Other "CTRP4" proteins (4)
SKU Description Size Price
PH307458 C1QTNF4 MS Standard C13 and N15-labeled recombinant protein (NP_114115) 10 ug
$3,360.00
LC410444 Lyophilized C1QTNF4 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY410444 Transient overexpression lysate of C1q and tumor necrosis factor related protein 4 (C1QTNF4) (as WB positive control) 100 ug
$436.00
TP701103 Purified recombinant protein of Human C1q and tumor necrosis factor related protein 4 (C1QTNF4), Leu17-End, with C-terminal His tag, secretory expressed in HEK293 cells, 50 ug 50 ug
$900.00

file-alt Citations

CTRP4 ameliorates inflammation, thereby attenuating the interaction between HUVECs and THP-1 monocytes through SIRT6/Nrf2 signaling
Sun, Ryu, Cho et al
Biochem Biophys Res Commun (2023) 691, 149293 DOI: 10.1016/j.bbrc.2023.149293
Cited by 4
AI Summary: OriGene’s human recombinant CTRP4 protein (Cat. No.: TP307458) was used in this study to investigate and demonstrate its anti-inflammatory effects on endothelial and monocyte interactions via the SIRT6/Nrf2 signaling pathway.
Snippet: CTRP4, identified as an adipokine, has demonstrated notable anti-inflammatory and anti-obesity effects in various disease models. …Human recombinant CTRP4 (Cat. No.: TP307458, OriGene, Rockville, MD,
Showing 1-1 of 1 papers.
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