AADAC (NM_001086) Human Recombinant Protein

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SKU
TP307111
Recombinant protein of human arylacetamide deacetylase (esterase) (AADAC), 20 µg
  $737.00
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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>RC207111 protein sequence
Red=Cloning site Green=Tags(s)

MGRKSLYLLIVGILIAYYIYTPLPDNVEEPWRMMWINAHLKTIQNLATFVELLGLHHFMDSFKVVGSFDE
VPPTSDENVTVTETKFNNILVRVYVPKRKSEALRRGLFYIHGGGWCVGSAALSGYDLLSRWTADRLDAVV
VSTNYRLAPKYHFPIQFEDVYNALRWFLRKKVLAKYGVNPERIGISGDSAGGNLAAAVTQQLLDDPDVKI
KLKIQSLIYPALQPLDVDLPSYQENSNFLFLSKSLMVRFWSEYFTTDRSLEKAMLSRQHVPVESSHLFKF
VNWSSLLPERFIKGHVYNNPNYGSSELAKKYPGFLDVRAAPLLADDNKLRGLPLTYVITCQYDLLRDDGL
MYVTRLRNTGVQVTHNHVEDGFHGAFSFLGLKISHRLINQYIEWLKENL

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-Myc/DDK
Predicted MW 45.6 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_001077
Locus ID 13
UniProt ID P22760
Cytogenetics 3q25.1
RefSeq Size 1725
RefSeq ORF 1197
Synonyms CES5A1; DAC
Summary Microsomal arylacetamide deacetylase competes against the activity of cytosolic arylamine N-acetyltransferase, which catalyzes one of the initial biotransformation pathways for arylamine and heterocyclic amine carcinogens provided by RefSeq, Jul 2008
Protein Categories Intracellular Proteins
Protein Families Druggable Genome, Transmembrane
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Other "AADAC" proteins (3)
SKU Description Size Price
PH307111 AADAC MS Standard C13 and N15-labeled recombinant protein (NP_001077) 10 ug
$3,360.00
LC421330 Lyophilized AADAC HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY421330 Transient overexpression lysate of arylacetamide deacetylase (esterase) (AADAC) (as WB positive control) 100 ug
$436.00

file-alt Citations

Influence of N-acetyltransferase 2 gene polymorphisms on the in vitro metabolism of the epidermal growth factor receptor inhibitor rociletinib
Ramirez, House, Ratain
Br J Clin Pharmacol (2021)
Cited by 3
AI Summary: OriGene’s recombinant human arylacetamide deacetylase (AADAC) protein was used in this study to assess its enzymatic activity in rociletinib metabolism experiments.
Snippet: NAT1) and sulfamethazine (for NAT2). Recombinant protein of human arylacetamide deacetylase (esterase) (AADAC) was obtained from OriGene Technologies, Inc. (Rockville, MD), and tested for enzymatic activity in our lab using the probe substrate rifampicin (see
Showing 1-1 of 1 papers.
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