ERp57 (PDIA3) (NM_005313) Human Recombinant Protein
SKU
TP305940
Recombinant protein of human protein disulfide isomerase family A, member 3 (PDIA3), 20 µg
$737.00
In Stock*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 54.2 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_005304 |
| Locus ID | 2923 |
| UniProt ID | P30101 |
| Cytogenetics | 15q15.3 |
| RefSeq Size | 3060 |
| RefSeq ORF | 1515 |
| Synonyms | ER60; ERp57; ERp60; ERp61; GRP57; GRP58; HEL-S-93n; HEL-S-269; HsT17083; P58; PI-PLC |
| Summary | This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase; however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates. This protein also functions as a molecular chaperone that prevents the formation of protein aggregates. provided by RefSeq, Dec 2016 |
| Protein Categories | Intracellular Proteins |
| Protein Families | Druggable Genome |
| Protein Pathways | Antigen processing and presentation |
Reviews
Documents
| FAQs |
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Resources
| Recombinant Protein Resources |
Other "ERp57" proteins (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH305940 | PDIA3 MS Standard C13 and N15-labeled recombinant protein (NP_005304) | 10 ug |
$3,360.00
|
|
| LC401637 | Lyophilized PDIA3 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY401637 | Transient overexpression lysate of protein disulfide isomerase family A, member 3 (PDIA3) (as WB positive control) | 100 ug |
$436.00
|
|
| TP721117 | Purified recombinant protein of Human protein disulfide isomerase family A, member 3 (PDIA3 | 10 ug |
$340.00
|
|
Citations
Protein disulfide isomerase plasma levels in healthy humans reveal proteomic signatures involved in contrasting endothelial phenotypes
Oliveira, Garcia-Rosa, Sachetto et al
Redox Biol (2019) 22, 101142 DOI: 10.1016/j.redox.2019.101142
Oliveira, Garcia-Rosa, Sachetto et al
Redox Biol (2019) 22, 101142 DOI: 10.1016/j.redox.2019.101142
Cited by 33
AI Summary: In this study, OriGene's Human P4HB (PDI) ELISA Kit (EA100907) was used to quantitatively measure plasma PDI levels, enabling the identification of distinct plasma proteome signatures associated with contrasting endothelial phenotypes in healthy individuals.
Proteína dissulfeto isomerase plasmática: detecção e correlação com assinaturas proteômicas ligadas a distintos fenótipos endoteliais em indivíduos saudáveis
Oliveira
Thesis (2019)
Oliveira
Thesis (2019)
Protein disulfide isomerase plasma levels in healthy humans reveal proteomic signatures involved in contrasting endothelial phenotypes
de Oliveira, Garcia-Rosa, Sachetto
Redox Biology (2019)
de Oliveira, Garcia-Rosa, Sachetto
Redox Biology (2019)
AI Summary: OriGene’s recombinant Erp57 (TP305940) and ERp5 (TP301710) proteins were used as reference standards in the analysis of plasma samples, enabling the study to accurately detect and quantify PDI family proteins and assess their association with distinct endothelial phenotypes.
Snippet: … Platelet-poor plasma (no dilution), recombinant PDI solutions (reduced, oxidized, S-nitrosylated), human cell lysates, conditioned medium, and recombinant Erp57 (OriGene-TP305940) and ERp5 (OriGene-TP301710) were analyzed. 2.3 PDI purification Histidine-tagged full length human PDI was cloned into the pET28a vector (Novagen) and overexpressed in E. coli strai;;... … Platelet-poor plasma (no dilution), recombinant PDI solutions (reduced, oxidized, S-nitrosylated), human cell lysates, conditioned medium, and recombinant Erp57 (OriGene-TP305940) and ERp5 (OriGene-TP301710) were analyzed. 2.3 PDI purification Histidine-tagged full length human PDI was cloned into the pET28a vector (Novagen) and overexpressed in E. coli strai;Platelet-poor plasma (no dilution), recombinant PDI solutions (reduced, oxidized, S-nitrosylated), human cell lysates, conditioned medium, and recombinant Erp57 (OriGene-TP305940) and ERp5 (OriGene-TP301710) were analyzed. 2.3. …
Showing 1-3 of 3 papers.
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