GRP78 (HSPA5) (NM_005347) Human Recombinant Protein

CAT#: TP305859

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Recombinant protein of human heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) (HSPA5)


 Product Datasheet for 'TP305859'

 Cited in 3 publications.

  View other "HSPA5" proteins (13)

USD 748.00


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Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) (HSPA5)
Species Human
Expression Host HEK293T
Expression cDNA Clone or AA Sequence Recombinant protein was produced with TrueORF clone, RC205859. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag C-Myc/DDK
Predicted MW 72.2 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Bioactivity Protein refolding (PMID: 28416388)
WB positive control (PMID: 28679661)
Ubiquitination substrate (PMID: 29260979)
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_005338
Locus ID 3309
Refseq Size 3973
Cytogenetics 9q33.3
Refseq ORF 1962
Synonyms BIP; GRP78; HEL-S-89n; MIF2
Summary The protein encoded by this gene is a member of the heat shock protein 70 (HSP70) family. It is localized in the lumen of the endoplasmic reticulum (ER), and is involved in the folding and assembly of proteins in the ER. As this protein interacts with many ER proteins, it may play a key role in monitoring protein transport through the cell. [provided by RefSeq, Sep 2010]
Protein Families Druggable Genome
Protein Pathways Antigen processing and presentation, Prion diseases

Citations (3)

Documents

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