Ribonuclease H2, subunit A (RNASEH2A) (NM_006397) Human Recombinant Protein
$737.00
In Stock*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 33.2 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_006388 |
| Locus ID | 10535 |
| UniProt ID | O75792 |
| Cytogenetics | 19p13.13 |
| RefSeq Size | 1148 |
| RefSeq ORF | 897 |
| Synonyms | AGS4; JUNB; RNASEHI; RNHIA; RNHL; THSD8 |
| Summary | The protein encoded by this gene is a component of the heterotrimeric type II ribonuclease H enzyme (RNAseH2). RNAseH2 is the major source of ribonuclease H activity in mammalian cells and endonucleolytically cleaves ribonucleotides. It is predicted to remove Okazaki fragment RNA primers during lagging strand DNA synthesis and to excise single ribonucleotides from DNA-DNA duplexes. Mutations in this gene cause Aicardi-Goutieres Syndrome (AGS), a an autosomal recessive neurological disorder characterized by progressive microcephaly and psychomotor retardation, intracranial calcifications, elevated levels of interferon-alpha and white blood cells in the cerebrospinal fluid.provided by RefSeq, Aug 2009 |
| Protein Categories | Immune system diseases, Intracellular Proteins |
| Protein Pathways | DNA replication |
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Resources
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Other "Ribonuclease H2, subunit A" proteins (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH304032 | RNASEH2A MS Standard C13 and N15-labeled recombinant protein (NP_006388) | 10 ug |
$3,360.00
|
|
| LC416666 | RNASEH2A HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY416666 | Transient overexpression lysate of ribonuclease H2, subunit A (RNASEH2A) | 100 ug |
$436.00
|
|
| TP762504 | Purified recombinant protein of Human ribonuclease H2, subunit A (RNASEH2A), full length, with N-terminal His tag, expressed in E.coli, 50ug | 50 ug |
$240.00
|
|
OriGene AI
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.