Ribonuclease H2, subunit A (RNASEH2A) (NM_006397) Human Mass Spec Standard

SKU
PH304032
RNASEH2A MS Standard C13 and N15-labeled recombinant protein (NP_006388)
  $3,360.00
3 Weeks*
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Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC204032
Predicted MW 33.4 kDa
Protein Sequence
Protein Sequence
>RC204032 protein sequence
Red=Cloning site Green=Tags(s)

MDLSELERDNTGRCRLSSPVPAVCRKEPCVLGVDEAGRGPVLGPMVYAICYCPLPRLADLEALKVADSKT
LLESERERLFAKMEDTDFVGWALDVLSPNLISTSMLGRVKYNLNSLSHDTATGLIQYALDQGVNVTQVFV
DTVGMPETYQARLQQSFPGIEVTVKAKADALYPVVSAASICAKVARDQAVKKWQFVEKLQDLDTDYGSGY
PNDPKTKAWLKEHVEPVFGFPQFVRFSWRTAQTILEKEAEDVIWEDSASENQEGLRKITSYFLNEGSQAR
PRSSHRYFLERGQESATSL

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_006388
RefSeq Size 1148
RefSeq ORF 897
Synonyms AGS4; JUNB; RNASEHI; RNHIA; RNHL; THSD8
Locus ID 10535
UniProt ID O75792
Cytogenetics 19p13.13
Summary The protein encoded by this gene is a component of the heterotrimeric type II ribonuclease H enzyme (RNAseH2). RNAseH2 is the major source of ribonuclease H activity in mammalian cells and endonucleolytically cleaves ribonucleotides. It is predicted to remove Okazaki fragment RNA primers during lagging strand DNA synthesis and to excise single ribonucleotides from DNA-DNA duplexes. Mutations in this gene cause Aicardi-Goutieres Syndrome (AGS), a an autosomal recessive neurological disorder characterized by progressive microcephaly and psychomotor retardation, intracranial calcifications, elevated levels of interferon-alpha and white blood cells in the cerebrospinal fluid.provided by RefSeq, Aug 2009
Protein Pathways DNA replication
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Documents
Resources
Other "Ribonuclease H2, subunit A" proteins (4)
SKU Description Size Price
LC416666 RNASEH2A HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY416666 Transient overexpression lysate of ribonuclease H2, subunit A (RNASEH2A) 100 ug
$436.00
TP304032 Recombinant protein of human ribonuclease H2, subunit A (RNASEH2A), 20 µg 20 ug
$737.00
TP762504 Purified recombinant protein of Human ribonuclease H2, subunit A (RNASEH2A), full length, with N-terminal His tag, expressed in E.coli, 50ug 50 ug
$240.00

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