LITAF (NM_004862) Human Recombinant Protein
SKU
TP303938
Recombinant protein of human lipopolysaccharide-induced TNF factor (LITAF), transcript variant 1, 20 µg
$867.00
In Stock*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 16.9 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_004853 |
| Locus ID | 9516 |
| UniProt ID | Q99732 |
| Cytogenetics | 16p13.13 |
| RefSeq Size | 2642 |
| RefSeq ORF | 483 |
| Synonyms | PIG7; SIMPLE; TP53I7 |
| Summary | Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppressor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene. provided by RefSeq, Dec 2014 |
| Protein Categories | Cytokines, Intracellular Proteins, Membrane Proteins, Nervous system: Neurodegenerative diseases |
| Protein Families | Druggable Genome, Transcription Factors |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "LITAF" proteins (7)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH303938 | LITAF MS Standard C13 and N15-labeled recombinant protein (NP_004853) | 10 ug |
$3,360.00
|
|
| LC417698 | Lyophilized LITAF HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC427883 | Lyophilized LITAF HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC427884 | Lyophilized LITAF HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY417698 | Transient overexpression lysate of lipopolysaccharide-induced TNF factor (LITAF), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
| LY427883 | Transient overexpression lysate of lipopolysaccharide-induced TNF factor (LITAF), transcript variant 2 (as WB positive control) | 100 ug |
$436.00
|
|
| LY427884 | Transient overexpression lysate of lipopolysaccharide-induced TNF factor (LITAF), transcript variant 3 (as WB positive control) | 100 ug |
$436.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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