Integrin beta 1(ITGB1) (NM_002211) Human Recombinant Protein
Recombinant protein of human integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) (ITGB1), transcript variant 1A
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|Description||Recombinant protein of human integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) (ITGB1), transcript variant 1A|
|Expression cDNA Clone or AA Sequence||Recombinant protein was produced with TrueORF clone, RC203818. Click on the TrueORF clone link to view cDNA and protein sequences.|
|Predicted MW||86.1 kDa|
|Concentration||>50 ug/mL as determined by microplate BCA method|
|Purity||> 80% as determined by SDS-PAGE and Coomassie blue staining|
|Buffer||25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. Store at –80C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.|
|Synonyms||CD29; FNRB; GPIIA; MDF2; MSK12; VLA-BETA; VLAB|
|Summary||Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2008].|
|Protein Families||ES Cell Differentiation/IPS, Transmembrane, Druggable Genome|
|Protein Pathways||Axon guidance, Focal adhesion, ECM-receptor interaction, Cell adhesion molecules (CAMs), Leukocyte transendothelial migration, Regulation of actin cytoskeleton, Pathogenic Escherichia coli infection, Pathways in cancer, Small cell lung cancer, Hypertrophic cardiomyopathy (HCM), Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy|