CCM2 (NM_031443) Human Recombinant Protein
SKU
TP301418
Recombinant protein of human cerebral cavernous malformation 2 (CCM2), transcript variant 2, 20 µg
$867.00
In Stock*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 48.7 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_113631 |
| Locus ID | 83605 |
| UniProt ID | Q9BSQ5 |
| Cytogenetics | 7p13 |
| RefSeq Size | 1904 |
| RefSeq ORF | 1332 |
| Synonyms | C7orf22; OSM; PP10187 |
| Summary | This gene encodes a scaffold protein that functions in the stress-activated p38 Mitogen-activated protein kinase (MAPK) signaling cascade. The protein interacts with SMAD specific E3 ubiquitin protein ligase 1 (also known as SMURF1) via a phosphotyrosine binding domain to promote RhoA degradation. The protein is required for normal cytoskeletal structure, cell-cell interactions, and lumen formation in endothelial cells. Mutations in this gene result in cerebral cavernous malformations. Multiple transcript variants encoding different isoforms have been found for this gene.provided by RefSeq, Nov 2009 |
| Protein Categories | Intracellular Proteins |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "CCM2" proteins (11)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH301418 | CCM2 MS Standard C13 and N15-labeled recombinant protein (NP_113631) | 10 ug |
$3,360.00
|
|
| LC410516 | Lyophilized CCM2 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC422467 | Lyophilized CCM2 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC425504 | Lyophilized CCM2 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC432927 | Lyophilized CCM2 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC432976 | Lyophilized CCM2 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY410516 | Transient overexpression lysate of cerebral cavernous malformation 2 (CCM2), transcript variant 2 (as WB positive control) | 100 ug |
$436.00
|
|
| LY422467 | Transient overexpression lysate of cerebral cavernous malformation 2 (CCM2), transcript variant 1 (as WB positive control) | 100 ug |
$665.00
|
|
| LY425504 | Transient overexpression lysate of cerebral cavernous malformation 2 (CCM2), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
| LY432927 | Transient overexpression lysate of cerebral cavernous malformation 2 (CCM2), transcript variant 4 (as WB positive control) | 100 ug |
$436.00
|
|
| LY432976 | Transient overexpression lysate of cerebral cavernous malformation 2 (CCM2), transcript variant 3 (as WB positive control) | 100 ug |
$436.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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