UNG (NM_080911) Human Mass Spec Standard

SKU
PH322868
UNG MS Standard C13 and N15-labeled recombinant protein (NP_550433)
  $3,360.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC222868
Predicted MW 34.5 kDa
Protein Sequence
Protein Sequence
>RC222868 representing NM_080911
Red=Cloning site Green=Tags(s)

MIGQKTLYSFFSPSPARKRHAPSPEPAVQGTGVAGVPEESGDAAAIPAKKAPAGQEEPGTPPSSPLSAEQ
LDRIQRNKAAALLRLAARNVPVGFGESWKKHLSGEFGKPYFIKLMGFVAEERKHYTVYPPPHQVFTWTQM
CDIKDVKVVILGQDPYHGPNQAHGLCFSVQRPVPPPPSLENIYKELSTDIEDFVHPGHGDLSGWAKQGVL
LLNAVLTVRAHQANSHKERGWEQFTDAVVSWLNQNSNGLVFLLWGSYAQKKGSAIDRKRHHVLQTAHPSP
LSVYRGFFGCRHFSKTNELLQKSGKKPIDWKEL

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_550433
RefSeq Size 2053
RefSeq ORF 939
Synonyms DGU; HIGM4; HIGM5; UDG; UNG1; UNG2; UNG15
Locus ID 7374
UniProt ID P13051
Cytogenetics 12q24.11
Summary This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases. provided by RefSeq, Nov 2010
Protein Families Druggable Genome, Stem cell - Pluripotency
Protein Pathways Base excision repair, Primary immunodeficiency
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Other "UNG" proteins (6)
SKU Description Size Price
LC408998 Lyophilized UNG HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC418736 Lyophilized UNG HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY408998 Transient overexpression lysate of uracil-DNA glycosylase (UNG), transcript variant 2 (as WB positive control) 100 ug
$436.00
LY418736 Transient overexpression lysate of uracil-DNA glycosylase (UNG), nuclear gene encoding mitochondrial protein, transcript variant 1 (as WB positive control) 100 ug
$436.00
TP322868 Recombinant protein of human uracil-DNA glycosylase (UNG), transcript variant 2, 20 µg 20 ug
$737.00
TP760178 Recombinant protein of human uracil-DNA glycosylase (UNG), nuclear gene encoding mitochondrial protein, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug 50 ug
$270.00

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