TPSG1 (NM_012467) Human Mass Spec Standard

SKU
PH322359
TPSG1 MS Standard C13 and N15-labeled recombinant protein (NP_036599)
  $3,360.00
3 Weeks*
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Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC222359
Predicted MW 33.76 kDa
Protein Sequence
Protein Sequence
>RC222359 representing NM_012467
Red=Cloning site Green=Tags(s)

MALGACGLLLLLAVPGVSLRTLQPGCGRPQVSDAGGRIVGGHAAPAGAWPWQASLRLRRMHVCGGSLLSP
QWVLTAAHCFSGSLNSSDYQVHLGELEITLSPHFSTVRQIILHSSPSGQPGTSGDIALVELSVPVTLSSR
ILPVCLPEASDDFCPGIRCSVTGWGYTREGEPLPPPYSLREVKVSVVDTETCRRDYPGPGGSILQPDMLC
ARGPGDACQDDSGGPLVCQVNGAWVQAGIVSWGEGCGRPNRPGVYTRVPAYVNWIRRHITASGGSESGYP
RLPLLAGFFLPGLFLLLVSCVLLAKCLLHPSADGTPFPAPD

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_036599
RefSeq Size 1124
RefSeq ORF 963
Synonyms PRSS31; TMT; trpA
Locus ID 25823
UniProt ID Q9NRR2
Cytogenetics 16p13.3
Summary Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. There is uncertainty regarding the number of genes in this cluster. Currently four functional genes - alpha I, beta I, beta II and gamma I - have been identified. And beta I has an allelic variant named alpha II, beta II has an allelic variant beta III, also gamma I has an allelic variant gamma II. Beta tryptases appear to be the main isoenzymes expressed in mast cells; whereas in basophils, alpha-tryptases predominant. This gene differs from other members of the tryptase gene family in that it has C-terminal hydrophobic domain, which may serve as a membrane anchor. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. provided by RefSeq, Jul 2008
Protein Families Druggable Genome, Transmembrane
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Other "TPSG1" proteins (3)
SKU Description Size Price
LC402219 Lyophilized TPSG1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY402219 Transient overexpression lysate of tryptase gamma 1 (TPSG1) (as WB positive control) 100 ug
$436.00
TP322359 Recombinant protein of human tryptase gamma 1 (TPSG1), 20 µg 20 ug
$867.00

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