Complement factor 8 beta (C8B) (NM_000066) Human Mass Spec Standard
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC219942 |
| Predicted MW | 67 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_000057 |
| RefSeq Size | 2178 |
| RefSeq ORF | 1773 |
| Synonyms | C82 |
| Locus ID | 732 |
| UniProt ID | P07358 |
| Cytogenetics | 1p32.2 |
| Summary | This gene encodes one of the three subunits of the complement component 8 (C8) protein. C8 is composed of equimolar amounts of alpha, beta and gamma subunits, which are encoded by three separate genes. C8 is one component of the membrane attack complex, which mediates cell lysis, and it initiates membrane penetration of the complex. This protein mediates the interaction of C8 with the C5b-7 membrane attack complex precursor. In humans deficiency of this protein is associated with increased risk of meningococcal infections. Alternative splicing results in multiple transcript variants. provided by RefSeq, Jun 2013 |
| Protein Families | Druggable Genome, Secreted Protein, Transmembrane |
| Protein Pathways | Complement and coagulation cascades, Prion diseases, Systemic lupus erythematosus |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "Complement factor 8 beta" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC424942 | Lyophilized C8B HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY424942 | Transient overexpression lysate of complement component 8, beta polypeptide (C8B) (as WB positive control) | 100 ug |
$665.00
|
|
| TP319942 | Recombinant protein of human complement component 8, beta polypeptide (C8B), 20 µg | 20 ug |
$737.00
|
|
Citations
Related Products
- Price:
- Actual Price:
Welcome to OriGene AI!
I'm your AI-powered guide to everything OriGene.
Ask me anything:
- Product specs
- Ordering help
- Technical questions
- How to find exactly what your experiment needs
Prefer a live agent? Connect with us by clicking the green chat icon, as seen in the image below or email our team at custsupport@origene.com.