P2X3 (P2RX3) (NM_002559) Human Mass Spec Standard

SKU
PH318626
P2RX3 MS Standard C13 and N15-labeled recombinant protein (NP_002550)
  $3,360.00
3 Weeks*
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Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC218626
Predicted MW 44.1 kDa
Protein Sequence
Protein Sequence
>RC218626 representing NM_002559
Red=Cloning site Green=Tags(s)

MNCISDFFTYETTKSVVVKSWTIGIINRVVQLLIISYFVGWVFLHEKAYQVRDTAIESSVVTKVKGSGLY
ANRVMDVSDYVTPPQGTSVFVIITKMIVTENQMQGFCPESEEKYRCVSDSQCGPERLPGGGILTGRCVNY
SSVLRTCEIQGWCPTEVDTVETPIMMEAENFTIFIKNSIRFPLFNFEKGNLLPNLTARDMKTCRFHPDKD
PFCPILRVGDVVKFAGQDFAKLARTGGVLGIKIGWVCDLDKAWDQCIPKYSFTRLDSVSEKSSVSPGYNF
RFAKYYKMENGSEYRTLLKAFGIRFDVLVYGNAGKFNIIPTIISSVAAFTSVGVGTVLCDIILLNFLKGA
DQYKAKKFEEVNETTLKIAALTNPVYPSDQTTVEKQSTDSGAFSIGH

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_002550
RefSeq Size 1349
RefSeq ORF 1191
Synonyms P2X3
Locus ID 5024
UniProt ID P56373
Cytogenetics 11q12.1
Summary This gene encodes a member of the P2X purinergic receptor (purinoceptor) gene family which includes seven members (P2RX1 - P2RX7). P2X purinoceptors are a family of cation-permeable, ligand-gated ion channels that open in response to the binding of extracellular adenosine 5'-triphosphate (ATP). The encoded protein is a subunit of the trimeric P2X3 receptor ion channel which is expressed by sensory or autonomic neurons. A deficiency of the orthologous protein in mice is associated with reduced pain-related behavior and urinary bladder hyporeflexia. provided by RefSeq, Aug 2017
Protein Families Druggable Genome, Ion Channels: ATP Receptors, Transmembrane
Protein Pathways Calcium signaling pathway, Neuroactive ligand-receptor interaction
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Other "P2X3" proteins (3)
SKU Description Size Price
LC419263 Lyophilized P2RX3 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY419263 Transient overexpression lysate of purinergic receptor P2X, ligand-gated ion channel, 3 (P2RX3) (as WB positive control) 100 ug
$436.00
TP318626 Recombinant protein of human purinergic receptor P2X, ligand-gated ion channel, 3 (P2RX3), 20 µg 20 ug
$867.00

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