P2X3 (P2RX3) (NM_002559) Human Mass Spec Standard
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC218626 |
| Predicted MW | 44.1 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_002550 |
| RefSeq Size | 1349 |
| RefSeq ORF | 1191 |
| Synonyms | P2X3 |
| Locus ID | 5024 |
| UniProt ID | P56373 |
| Cytogenetics | 11q12.1 |
| Summary | This gene encodes a member of the P2X purinergic receptor (purinoceptor) gene family which includes seven members (P2RX1 - P2RX7). P2X purinoceptors are a family of cation-permeable, ligand-gated ion channels that open in response to the binding of extracellular adenosine 5'-triphosphate (ATP). The encoded protein is a subunit of the trimeric P2X3 receptor ion channel which is expressed by sensory or autonomic neurons. A deficiency of the orthologous protein in mice is associated with reduced pain-related behavior and urinary bladder hyporeflexia. provided by RefSeq, Aug 2017 |
| Protein Families | Druggable Genome, Ion Channels: ATP Receptors, Transmembrane |
| Protein Pathways | Calcium signaling pathway, Neuroactive ligand-receptor interaction |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "P2X3" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC419263 | Lyophilized P2RX3 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY419263 | Transient overexpression lysate of purinergic receptor P2X, ligand-gated ion channel, 3 (P2RX3) (as WB positive control) | 100 ug |
$436.00
|
|
| TP318626 | Recombinant protein of human purinergic receptor P2X, ligand-gated ion channel, 3 (P2RX3), 20 µg | 20 ug |
$867.00
|
|
Citations
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