CAMLG (NM_001745) Human Mass Spec Standard
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC218292 |
| Predicted MW | 33 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_001736 |
| RefSeq Size | 2255 |
| RefSeq ORF | 888 |
| Synonyms | CAML; GET2 |
| Locus ID | 819 |
| UniProt ID | P49069 |
| Cytogenetics | 5q31.1 |
| Summary | The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin. provided by RefSeq, Jul 2008 |
| Protein Families | Druggable Genome |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "CAMLG" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC419768 | Lyophilized CAMLG HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY419768 | Transient overexpression lysate of calcium modulating ligand (CAMLG) (as WB positive control) | 100 ug |
$436.00
|
|
| TP318292 | Recombinant protein of human calcium modulating ligand (CAMLG), 20 µg | 20 ug |
$867.00
|
|
Citations
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