IMPDH1 (NM_000883) Human Mass Spec Standard

SKU
PH315206
IMPDH1 MS Standard C13 and N15-labeled recombinant protein (NP_000874)
  $3,360.00
3 Weeks*
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Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC215206
Predicted MW 64.1 kDa
Protein Sequence
Protein Sequence
>RC215206 representing NM_000883
Red=Cloning site Green=Tags(s)

MEGPLTPPPLQGGGAAAVPEPGARQHPGHETAAQRYSARLLQAGYEPESPRLDLATHPTTPRSELSSVVL
LAGVGVQMDRLRRASMADYLISGGTGYVPEDGLTAQQLFASADGLTYNDFLILPGFIDFIADEVDLTSAL
TRKITLKTPLISSPMDTVTEADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSH
TVGDVLEAKMRHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAPAGVTLK
EANEILQRSKKGKLPIVNDCDELVAIIARTDLKKNRDYPLASKDSQKQLLCGAAVGTREDDKYRLDLLTQ
AGVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLIDAGVDGLRVGMGCGSICITQE
VMACGRPQGTAVYKVAEYARRFGVPIIADGGIQTVGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDG
VRLKKYRGMGSLDAMEKSSSSQKRYFSEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARS
LSVLRSMMYSGELKFEKRTMSAQIEGGVHGLHSYEKRLY

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_000874
RefSeq Size 2880
RefSeq ORF 1797
Synonyms IMPD; IMPD1; IMPDH-I; LCA11; RP10; sWSS2608
Locus ID 3614
UniProt ID P20839
Cytogenetics 7q32.1
Summary The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Dec 2008
Protein Families Druggable Genome
Protein Pathways Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism
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Other "IMPDH1" proteins (13)
SKU Description Size Price
PH307118 IMPDH1 MS Standard C13 and N15-labeled recombinant protein (NP_899066) 10 ug
$3,360.00
LC400315 Lyophilized IMPDH1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC405238 Lyophilized IMPDH1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC420173 Lyophilized IMPDH1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC428185 Lyophilized IMPDH1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC428186 Lyophilized IMPDH1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY400315 Transient overexpression lysate of IMP (inosine monophosphate) dehydrogenase 1 (IMPDH1), transcript variant 1 (as WB positive control) 100 ug
$665.00
LY405238 Transient overexpression lysate of IMP (inosine monophosphate) dehydrogenase 1 (IMPDH1), transcript variant 2 (as WB positive control) 100 ug
$436.00
LY420173 Transient overexpression lysate of IMP (inosine monophosphate) dehydrogenase 1 (IMPDH1), transcript variant 3 (as WB positive control) 100 ug
$665.00
LY428185 Transient overexpression lysate of IMP (inosine monophosphate) dehydrogenase 1 (IMPDH1), transcript variant 7 (as WB positive control) 100 ug
$436.00
LY428186 Transient overexpression lysate of IMP (inosine monophosphate) dehydrogenase 1 (IMPDH1), transcript variant 4 (as WB positive control) 100 ug
$436.00
TP307118 Recombinant protein of human IMP (inosine monophosphate) dehydrogenase 1 (IMPDH1), transcript variant 2, 20 µg 20 ug
$867.00
TP315206 Recombinant protein of human IMP (inosine monophosphate) dehydrogenase 1 (IMPDH1), transcript variant 1, 20 µg 20 ug
$867.00

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