VPS4A (NM_013245) Human Mass Spec Standard

SKU
PH308099
VPS4A MS Standard C13 and N15-labeled recombinant protein (NP_037377)
  $3,360.00
3 Weeks*
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Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC208099
Predicted MW 48.9 kDa
Protein Sequence
Protein Sequence
>RC208099 protein sequence
Red=Cloning site Green=Tags(s)

MTTSTLQKAIDLVTKATEEDKAKNYEEALRLYQHAVEYFLHAIKYEAHSDKAKESIRAKCVQYLDRAEKL
KDYLRSKEKHGKKPVKENQSEGKGSDSDSEGDNPEKKKLQEQLMGAVVMEKPNIRWNDVAGLEGAKEALK
EAVILPIKFPHLFTGKRTPWRGILLFGPPGTGKSYLAKAVATEANNSTFFSVSSSDLMSKWLGESEKLVK
NLFELARQHKPSIIFIDEVDSLCGSRNENESEAARRIKTEFLVQMQGVGNNNDGTLVLGATNIPWVLDSA
IRRRFEKRIYIPLPEEAARAQMFRLHLGSTPHNLTDANIHELARKTEGYSGADISIIVRDSLMQPVRKVQ
SATHFKKVCGPSRTNPSMMIDDLLTPCSPGDPGAMEMTWMDVPGDKLLEPVVCMSDMLRSLATTRPTVNA
DDLLKVKKFSEDFGQES

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_037377
RefSeq Size 2211
RefSeq ORF 1311
Synonyms CIMDAG; SKD1; SKD1A; SKD2; VPS4; VPS4-1
Locus ID 27183
UniProt ID Q9UN37
Cytogenetics 16q22.1
Summary The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. The mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be really an yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 16; the gene for the other resides on chromosome 18. provided by RefSeq, Jul 2008
Protein Pathways Endocytosis
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Documents
Resources
Other "VPS4A" proteins (3)
SKU Description Size Price
LC415707 Lyophilized VPS4A HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY415707 Transient overexpression lysate of vacuolar protein sorting 4 homolog A (S. cerevisiae) (VPS4A) (as WB positive control) 100 ug
$436.00
TP308099 Recombinant protein of human vacuolar protein sorting 4 homolog A (S. cerevisiae) (VPS4A), 20 µg 20 ug
$737.00

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