COX5A (NM_004255) Human Mass Spec Standard

SKU
PH306046
COX5A MS Standard C13 and N15-labeled recombinant protein (NP_004246)
  $3,360.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC206046
Predicted MW 16.8 kDa
Protein Sequence
Protein Sequence
>RC206046 protein sequence
Red=Cloning site Green=Tags(s)

MLGAALRRCAVAATTRADPRGLLHSARTPGPAVAIQSVRCYSHGSQETDEEFDARWVTYFNKPDIDAWEL
RKGINTLVTYDMVPEPKIIDAALRACRRLNDFASTVRILEVVKDKAGPHKEIYPYVIQELRPTLNELGIS
TPEELGLDKV

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_004246
RefSeq Size 784
RefSeq ORF 450
Synonyms COX; COX-VA; MC4DN20; VA
Locus ID 9377
UniProt ID P20674
Cytogenetics 15q24.2
Summary Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer of proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit Va of the human mitochondrial respiratory chain enzyme. A pseudogene COX5AP1 has been found in chromosome 14q22. provided by RefSeq, Jul 2008
Protein Pathways Alzheimer's disease, Cardiac muscle contraction, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease
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Other "COX5A" proteins (3)
SKU Description Size Price
LC418109 Lyophilized COX5A HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY418109 Transient overexpression lysate of cytochrome c oxidase subunit Va (COX5A), nuclear gene encoding mitochondrial protein (as WB positive control) 100 ug
$436.00
TP306046 Recombinant protein of human cytochrome c oxidase subunit Va (COX5A), nuclear gene encoding mitochondrial protein, 20 µg 20 ug
$737.00

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