CHAC2 (NM_001008708) Human Mass Spec Standard

SKU PH305083

CHAC2 MS Standard C13 and N15-labeled recombinant protein (NP_001008708)

Product Data

• Tag: C-Myc/DDK
• Species: Human
• Expression Host: HEK293
• Expression cDNA Clone or AA Sequence: [RC205083]
• Predicted MW: 20.9 kDa
• Protein Sequence:
  Protein Sequence

  >RC205083 protein sequence; Red=Cloning site Green=Tags(s); ; MWVFGYGSLIWKVDFPYQDKLVGYITNYSRRFWQGSTDHRGVPGKPGRVVTLVEDPAGCVWGVAYRLPVG; KEEEVKAYLDFREKGGYRTTTVIFYPKDPTTKPFSVLLYIGTCDNPDYLGPAPLEDIAEQIFNAAGPSGR; NTEYLFELANSIRNLVPEEADEHLFALEKLVKERLEGKQNLNCI; ; TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >0.05 µg/µL as determined by microplate BCA method
• Labeling Method: Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
• Buffer: 25 mM Tris-HCl, 100 mM glycine, pH 7.3
• Storage: Store at -80°C. Avoid repeated freeze-thaw cycles.
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Shipping: Dry Ice

Reference Data

• RefSeq: NP_001008708
• RefSeq Size: 1305
• RefSeq ORF: 552
• Synonyms: GCG1
• Locus ID: 494143
• UniProt ID: Q8WUX2
• Cytogenetics: 2p16.2
• Summary: The protein encoded by this gene is a gamma-glutamyl cyclotransferase that catalyzes the conversion of glutathione to 5-oxoproline and cysteinylglycine. It is thought that this gene is upregulated in response to endoplasmic reticulum stress and that the glutathione depletion enhances apoptosis. [provided by RefSeq, Sep 2016]