CA12 (NM_001218) Human Mass Spec Standard

SKU
PH304810
CA12 MS Standard C13 and N15-labeled recombinant protein (NP_001209)
  $3,360.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC204810
Predicted MW 39.5 kDa
Protein Sequence
Protein Sequence
>RC204810 protein sequence
Red=Cloning site Green=Tags(s)

MPRRSLHAAAVLLLVILKEQPSSPAPVNGSKWTYFGPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDAS
LTPLEFQGYNLSANKQFLLTNNGHSVKLNLPSDMHIQGLQSRYSATQLHLHWGNPNDPHGSEHTVSGQHF
AAELHIVHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFNPSYDKIFSHLQHVKYKGQEAFVPGFNIEEL
LPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKF
DERLVYTSFSQVQVCTAAGLSLGIILSLALAGILGICIVVVVSIWLFRRKSIKKGDNKGVIYKPATKMET
EAHA

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_001209
RefSeq Size 4209
RefSeq ORF 1062
Synonyms CA-XII; CAXII; HsT18816; T18816
Locus ID 771
UniProt ID O43570
Cytogenetics 15q22.2
Summary Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. This gene product is a type I membrane protein that is highly expressed in normal tissues, such as kidney, colon and pancreas, and has been found to be overexpressed in 10% of clear cell renal carcinomas. Three transcript variants encoding different isoforms have been identified for this gene. provided by RefSeq, Jun 2014
Protein Families Druggable Genome, Transmembrane
Protein Pathways Nitrogen metabolism
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Other "CA12" proteins (5)
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LC400487 Lyophilized CA12 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
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LC404173 Lyophilized CA12 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
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LY400487 Transient overexpression lysate of carbonic anhydrase XII (CA12), transcript variant 1 (as WB positive control) 100 ug
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LY404173 Transient overexpression lysate of carbonic anhydrase XII (CA12), transcript variant 2 (as WB positive control) 100 ug
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TP304810 Recombinant protein of human carbonic anhydrase XII (CA12), transcript variant 1, 20 µg 20 ug
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