CDK2AP1 (NM_004642) Human Mass Spec Standard
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC204442 |
| Predicted MW | 12.4 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_004633 |
| RefSeq Size | 1655 |
| RefSeq ORF | 345 |
| Synonyms | doc-1; DOC1; DORC1; p12DOC-1; ST19 |
| Locus ID | 8099 |
| UniProt ID | O14519 |
| Cytogenetics | 12q24.31 |
| Summary | The protein encoded by this gene is a cyclin-dependent kinase 2 (CDK2) -associated protein which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggests a regulatory role in DNA replication during the S-phase of the cell cycle. This protein also forms a core subunit of the nucleosome remodeling and histone deacetylation (NURD) complex that epigenetically regulates embryonic stem cell differentiation. This gene thus plays a role in both cell-cycle and epigenetic regulation. Alternative splicing results in multiple transcript variants encoding distinct isoforms. provided by RefSeq, Jul 2012 |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "CDK2AP1" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC401472 | Lyophilized CDK2AP1 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY401472 | Transient overexpression lysate of cyclin-dependent kinase 2 associated protein 1 (CDK2AP1) (as WB positive control) | 100 ug |
$436.00
|
|
| TP304442 | Recombinant protein of human cyclin-dependent kinase 2 associated protein 1 (CDK2AP1), 20 µg | 20 ug |
$867.00
|
|
Citations
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