CDK2AP1 (NM_004642) Human Mass Spec Standard

SKU
PH304442
CDK2AP1 MS Standard C13 and N15-labeled recombinant protein (NP_004633)
  $3,360.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC204442
Predicted MW 12.4 kDa
Protein Sequence
Protein Sequence
>RC204442 protein sequence
Red=Cloning site Green=Tags(s)

MSYKPNLAAHMPAAALNAAGSVHSPSTSMATSSQYRQLLSDYGPPSLGYTQGTGNSQVPQSKYAELLAII
EELGKEIRPTYAGSKSAMERLKRGIIHARGLVRECLAETERNARS

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_004633
RefSeq Size 1655
RefSeq ORF 345
Synonyms doc-1; DOC1; DORC1; p12DOC-1; ST19
Locus ID 8099
UniProt ID O14519
Cytogenetics 12q24.31
Summary The protein encoded by this gene is a cyclin-dependent kinase 2 (CDK2) -associated protein which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggests a regulatory role in DNA replication during the S-phase of the cell cycle. This protein also forms a core subunit of the nucleosome remodeling and histone deacetylation (NURD) complex that epigenetically regulates embryonic stem cell differentiation. This gene thus plays a role in both cell-cycle and epigenetic regulation. Alternative splicing results in multiple transcript variants encoding distinct isoforms. provided by RefSeq, Jul 2012
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Other "CDK2AP1" proteins (3)
SKU Description Size Price
LC401472 Lyophilized CDK2AP1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY401472 Transient overexpression lysate of cyclin-dependent kinase 2 associated protein 1 (CDK2AP1) (as WB positive control) 100 ug
$436.00
TP304442 Recombinant protein of human cyclin-dependent kinase 2 associated protein 1 (CDK2AP1), 20 µg 20 ug
$867.00

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