SF3B5 (NM_031287) Human Mass Spec Standard

SKU
PH300977
SF3B5 MS Standard C13 and N15-labeled recombinant protein (NP_112577)
  $3,360.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC200977
Predicted MW 10.1 kDa
Protein Sequence
Protein Sequence
>RC200977 protein sequence
Red=Cloning site Green=Tags(s)

MTDRYTIHSQLEHLQSKYIGTGHADTTKWEWLVNQHRDSYCSYMGHFDLLNYFAIAENESKARVRFNLME
KMLQPCGPPADKPEEN

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_112577
RefSeq Size 786
RefSeq ORF 258
Synonyms SF3b10; Ysf3
Locus ID 83443
UniProt ID Q9BWJ5
Cytogenetics 6q24.2
Summary Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex, a constituent of the spliceosome (PubMed:27720643, PubMed:28781166). SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA (PubMed:12234937).UniProtKB/Swiss-Prot Function
Protein Pathways Spliceosome
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Other "SF3B5" proteins (3)
SKU Description Size Price
LC410578 Lyophilized SF3B5 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY410578 Transient overexpression lysate of splicing factor 3b, subunit 5, 10kDa (SF3B5) (as WB positive control) 100 ug
$436.00
TP300977 Recombinant protein of human splicing factor 3b, subunit 5, 10kDa (SF3B5), 20 µg 20 ug
$867.00

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