OTUD5 (NM_017602) Human Mass Spec Standard

SKU
PH300893
OTUD5 MS Standard C13 and N15-labeled recombinant protein (NP_060072)
  $3,360.00
3 Weeks*
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Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC200893
Predicted MW 60.4 kDa
Protein Sequence
Protein Sequence
>RC200893 representing NM_017602
Red=Cloning site Green=Tags(s)

MTILPKKKPPPPDADPANEPPPPGPMPPAPRRGGGVGVGGGGTGVGGGDRDRDSGVVGARPRASPPPQGP
LPGPPGALHRWALAVPPGAVAGPRPQQASPPPCGGPGGPGGGPGDALGAAAAGVGAAGVVVGVGGAVGVG
GCCSGPGHSKRRRQAPGVGAVGGGSPEREEVGAGYNSEDEYEAAAARIEAMDPATVEQQEHWFEKALRDK
KGFIIKQMKEDGACLFRAVADQVYGDQDMHEVVRKHCMDYLMKNADYFSNYVTEDFTTYINRKRKNNCHG
NHIEMQAMAEMYNRPVEVYQYSTGTSAVEPINTFHGIHQNEDEPIRVSYHRNIHYNSVVNPNKATIGVGL
GLPSFKPGFAEQSLMKNAIKTSEESWIEQQMLEDKKRATDWEATNEAIEEQVARESYLQWLRDQEKQARQ
VRGPSQPRKASATCSSATAAASSGLEEWTSRSPRQRSSASSPEHPELHAELGMKPPSPGTVLALAKPPSP
CAPGTSSQFSAGADRATSPLVSLYPALECRALIQQMSPSAFGLNDWDDDEILASVLAVSQQEYLDSMKKN
KVHRDPPPDKS

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_060072
RefSeq Size 2759
RefSeq ORF 1713
Synonyms DUBA; MCAND
Locus ID 55593
UniProt ID Q96G74
Cytogenetics Xp11.23
Summary This gene encodes a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily. The OTU domain confers deubiquitinase activity and the encoded protein has been shown to suppress the type I interferon-dependent innate immune response by cleaving the polyubiquitin chain from an essential type I interferon adaptor protein. Cleavage results in disassociation of the adaptor protein from a downstream signaling complex and disruption of the type I interferon signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been described. provided by RefSeq, Oct 2008
Protein Families Protease
Protein Pathways RIG-I-like receptor signaling pathway
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Documents
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Other "OTUD5" proteins (9)
SKU Description Size Price
LC413689 Lyophilized OTUD5 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC427830 Lyophilized OTUD5 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC427831 Lyophilized OTUD5 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC427832 Lyophilized OTUD5 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY413689 Transient overexpression lysate of OTU domain containing 5 (OTUD5), transcript variant 1 (as WB positive control) 100 ug
$436.00
LY427830 Transient overexpression lysate of OTU domain containing 5 (OTUD5), transcript variant 2 (as WB positive control) 100 ug
$436.00
LY427831 Transient overexpression lysate of OTU domain containing 5 (OTUD5), transcript variant 3 (as WB positive control) 100 ug
$436.00
LY427832 Transient overexpression lysate of OTU domain containing 5 (OTUD5), transcript variant 4 (as WB positive control) 100 ug
$436.00
TP300893 Recombinant protein of human OTU domain containing 5 (OTUD5), transcript variant 1, 20 µg 20 ug
$737.00

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