GDI2 (NM_001494) Human Mass Spec Standard
$3,360.00
3 Weeks*
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC200596 |
| Predicted MW | 50.7 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_001485 |
| RefSeq Size | 2441 |
| RefSeq ORF | 1335 |
| Synonyms | HEL-S-46e; RABGDIB |
| Locus ID | 2665 |
| UniProt ID | P50395 |
| Cytogenetics | 10p15.1 |
| Summary | GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI2 is ubiquitously expressed. The GDI2 gene contains many repetitive elements indicating that it may be prone to inversion/deletion rearrangements. Alternative splicing results in multiple transcript variants encoding distinct isoforms. provided by RefSeq, Jul 2008 |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "GDI2" proteins (5)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC400572 | Lyophilized GDI2 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC426526 | Lyophilized GDI2 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY400572 | Transient overexpression lysate of GDP dissociation inhibitor 2 (GDI2), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
| LY426526 | Transient overexpression lysate of GDP dissociation inhibitor 2 (GDI2), transcript variant 2 (as WB positive control) | 100 ug |
$436.00
|
|
| TP300596 | Recombinant protein of human GDP dissociation inhibitor 2 (GDI2), transcript variant 1, 20 µg | 20 ug |
$867.00
|
|
Citations
Adipose tissue depot-specific intracellular and extracellular cues contributing to insulin resistance in obese individuals
Guzmán-Ruiz, Tercero-Alcázar, Rabanal-Ruiz et al
FASEB J. (2020)
Guzmán-Ruiz, Tercero-Alcázar, Rabanal-Ruiz et al
FASEB J. (2020)
AI Summary: OriGene contributed to this study by providing the DsRed-GDI2 plasmid (NM_001494), which was used for overexpression experiments to investigate the role of GDI2 in adipocyte function related to insulin resistance.
Snippet: For overexpression studies, 3T3-L1 adipocytes (D6) on 150-mm Petri dishes were electroporated using either a DsRed or CFP empty vectors or containing the coding sequence of the GDP dissociation inhibitor of Rab proteins, GDI2 (NM_001494;Origene, Madrid, Spain) (DsRed-GDI2) (50 µg), following our established procedures.22,26 Thereafter, cells were cultured for 48 hours, and then, processed for confocal microscopy and functional studies (see below)
Showing 1-1 of 1 papers.
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